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Growth cone-specific functions of XMAP215 in restricting microtubule dynamics and promoting axonal outgrowth

BACKGROUND: Microtubule (MT) regulators play essential roles in multiple aspects of neural development. In vitro reconstitution assays have established that the XMAP215/Dis1/TOG family of MT regulators function as MT ‘plus-end-tracking proteins’ (+TIPs) that act as processive polymerases to drive MT...

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Detalles Bibliográficos
Autores principales: Lowery, Laura Anne, Stout, Alina, Faris, Anna E, Ding, Liya, Baird, Michelle A, Davidson, Michael W, Danuser, Gaudenz, Van Vactor, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907036/
https://www.ncbi.nlm.nih.gov/pubmed/24289819
http://dx.doi.org/10.1186/1749-8104-8-22