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Focused, high accuracy 5-methylcytosine quantitation with base resolution by benchtop next-generation sequencing
BACKGROUND: The growing interest in the role of epigenetic modifications in human health and disease has led to the development of next-generation sequencing methods for whole genome analysis of DNA methylation patterns. However, many projects require targeted methylation analysis of specific genes...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907040/ https://www.ncbi.nlm.nih.gov/pubmed/24279302 http://dx.doi.org/10.1186/1756-8935-6-33 |