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DNA Methylation is Associated with an Increased Level of Conservation at Nondegenerate Nucleotides in Mammals
DNA methylation at CpG dinucleotides can significantly increase the rate of cytosine-to-thymine mutations and the level of sequence divergence. Although the correlations between DNA methylation and genomic sequence evolution have been widely studied, an unaddressed yet fundamental question is how DN...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907051/ https://www.ncbi.nlm.nih.gov/pubmed/24157417 http://dx.doi.org/10.1093/molbev/mst208 |