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DNA Methylation is Associated with an Increased Level of Conservation at Nondegenerate Nucleotides in Mammals

DNA methylation at CpG dinucleotides can significantly increase the rate of cytosine-to-thymine mutations and the level of sequence divergence. Although the correlations between DNA methylation and genomic sequence evolution have been widely studied, an unaddressed yet fundamental question is how DN...

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Detalles Bibliográficos
Autores principales: Chuang, Trees-Juen, Chen, Feng-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907051/
https://www.ncbi.nlm.nih.gov/pubmed/24157417
http://dx.doi.org/10.1093/molbev/mst208

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