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Rapid Creation of Forward-Genetics Tools for C. briggsae Using TALENs: Lessons for Nonmodel Organisms

Although evolutionary studies of gene function often rely on RNA interference, the ideal approach would use reverse genetics to create null mutations for cross-species comparisons and forward genetics to identify novel genes in each species. We have used transcription activator-like effector nucleas...

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Detalles Bibliográficos
Autores principales: Wei, Qing, Shen, Yongquan, Chen, Xiangmei, Shifman, Yelena, Ellis, Ronald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907053/
https://www.ncbi.nlm.nih.gov/pubmed/24194560
http://dx.doi.org/10.1093/molbev/mst213