The shaping and functional consequences of the dosage effect landscape in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a malignant proliferation of plasma B cells. Based on recurrent aneuploidy such as copy number alterations (CNAs), myeloma is divided into two subtypes with different CNA patterns and patient survival outcomes. How aneuploidy events arise, and whether they contri...

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Detalles Bibliográficos
Autores principales: Samur, Mehmet K, Shah, Parantu K, Wang, Xujun, Minvielle, Stéphane, Magrangeas, Florence, Avet-Loiseau, Hervé, Munshi, Nikhil C, Li, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907079/
https://www.ncbi.nlm.nih.gov/pubmed/24088394
http://dx.doi.org/10.1186/1471-2164-14-672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907079/
https://www.ncbi.nlm.nih.gov/pubmed/24088394
http://dx.doi.org/10.1186/1471-2164-14-672

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