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Relative resistance of HIV-1 founder viruses to control by interferon-alpha

BACKGROUND: Following mucosal human immunodeficiency virus type 1 (HIV-1) transmission, type 1 interferons (IFNs) are rapidly induced at sites of initial virus replication in the mucosa and draining lymph nodes. However, the role played by IFN-stimulated antiviral activity in restricting HIV-1 repli...

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Detalles Bibliográficos
Autores principales: Fenton-May, Angharad E, Dibben, Oliver, Emmerich, Tanja, Ding, Haitao, Pfafferott, Katja, Aasa-Chapman, Marlen M, Pellegrino, Pierre, Williams, Ian, Cohen, Myron S, Gao, Feng, Shaw, George M, Hahn, Beatrice H, Ochsenbauer, Christina, Kappes, John C, Borrow, Persephone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907080/
https://www.ncbi.nlm.nih.gov/pubmed/24299076
http://dx.doi.org/10.1186/1742-4690-10-146