Rethinking metabotropic glutamate receptor 5 pathological findings in psychiatric disorders: implications for the future of novel therapeutics

BACKGROUND: Pharmacological modulation of metabotropic glutamate receptor 5 (mGluR5) is of marked interest as a novel therapeutic mechanism to treat schizophrenia and major depression. However, the status of mGluR5 in the pathophysiology of these disorders remains unknown. DISCUSSION: The majority o...

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Detalles Bibliográficos
Autores principales: Newell, Kelly A, Matosin, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Debate
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907147/
https://www.ncbi.nlm.nih.gov/pubmed/24472577
http://dx.doi.org/10.1186/1471-244X-14-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907147/
https://www.ncbi.nlm.nih.gov/pubmed/24472577
http://dx.doi.org/10.1186/1471-244X-14-23

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