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Rethinking metabotropic glutamate receptor 5 pathological findings in psychiatric disorders: implications for the future of novel therapeutics

BACKGROUND: Pharmacological modulation of metabotropic glutamate receptor 5 (mGluR5) is of marked interest as a novel therapeutic mechanism to treat schizophrenia and major depression. However, the status of mGluR5 in the pathophysiology of these disorders remains unknown. DISCUSSION: The majority o...

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Detalles Bibliográficos
Autores principales:	Newell, Kelly A, Matosin, Natalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Debate
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907147/ https://www.ncbi.nlm.nih.gov/pubmed/24472577 http://dx.doi.org/10.1186/1471-244X-14-23

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