Excess CD40L does not rescue anti-DNA B cells from clonal anergy

CD40L, a member of the tumor necrosis factor (TNF) ligand family, is overexpressed in patients with systemic lupus erythematosus and in lupus mouse models. Previously, we demonstrated that B cells producing pathogenic anti-Sm/RNP antibodies are deleted in the splenic marginal zone (MZ), and that MZ...

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Detalles Bibliográficos
Autores principales: Aslam, Mohammad, Kishi, Yusuke, Tsubata, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907155/
https://www.ncbi.nlm.nih.gov/pubmed/24627791
http://dx.doi.org/10.12688/f1000research.2-218.v2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907155/
https://www.ncbi.nlm.nih.gov/pubmed/24627791
http://dx.doi.org/10.12688/f1000research.2-218.v2

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