Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma

Follicular lymphoma (FL) is an incurable malignancy(1), with transformation to an aggressive subtype being a critical event during disease progression. Here we performed whole genome or exome sequencing on 10 FL-transformed FL pairs, followed by deep sequencing of 28 genes in an extension cohort and...

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Detalles Bibliográficos
Autores principales: Okosun, Jessica, Bödör, Csaba, Wang, Jun, Araf, Shamzah, Yang, Cheng-Yuan, Pan, Chenyi, Boller, Sören, Cittaro, Davide, Bozek, Monika, Iqbal, Sameena, Matthews, Janet, Wrench, David, Marzec, Jacek, Tawana, Kiran, Popov, Nikolay, O’Riain, Ciaran, O’Shea, Derville, Carlotti, Emanuela, Davies, Andrew, Lawrie, Charles H., Matolcsy, Andras, Calaminici, Maria, Norton, Andrew, Byers, Richard J., Mein, Charles, Stupka, Elia, Lister, T. Andrew, Lenz, Georg, Montoto, Silvia, Gribben, John G., Fan, Yuhong, Grosschedl, Rudolf, Chelala, Claude, Fitzgibbon, Jude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907271/
https://www.ncbi.nlm.nih.gov/pubmed/24362818
http://dx.doi.org/10.1038/ng.2856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907271/
https://www.ncbi.nlm.nih.gov/pubmed/24362818
http://dx.doi.org/10.1038/ng.2856

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