Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts

The function of osteoclasts (OCs), multinucleated giant cells (MGCs) of the monocytic lineage, is bone resorption. To resorb bone, OCs form podosomes. These are actin-rich adhesive structures that pattern into rings that drive OC migration and into “sealing-zones” (SZs) that confine the resorption l...

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Detalles Bibliográficos
Autores principales: Georgess, Dan, Mazzorana, Marlène, Terrado, José, Delprat, Christine, Chamot, Christophe, Guasch, Rosa M., Pérez-Roger, Ignacio, Jurdic, Pierre, Machuca-Gayet, Irma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907278/
https://www.ncbi.nlm.nih.gov/pubmed/24284899
http://dx.doi.org/10.1091/mbc.E13-07-0363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907278/
https://www.ncbi.nlm.nih.gov/pubmed/24284899
http://dx.doi.org/10.1091/mbc.E13-07-0363

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