A Model for the Epigenetic Switch Linking Inflammation to Cell Transformation: Deterministic and Stochastic Approaches

Recently, a molecular pathway linking inflammation to cell transformation has been discovered. This molecular pathway rests on a positive inflammatory feedback loop between NF-κB, Lin28, Let-7 microRNA and IL6, which leads to an epigenetic switch allowing cell transformation. A transient activation...

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Detalles Bibliográficos
Autores principales: Gérard, Claude, Gonze, Didier, Lemaigre, Frédéric, Novák, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907303/
https://www.ncbi.nlm.nih.gov/pubmed/24499937
http://dx.doi.org/10.1371/journal.pcbi.1003455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907303/
https://www.ncbi.nlm.nih.gov/pubmed/24499937
http://dx.doi.org/10.1371/journal.pcbi.1003455

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