Age, Gender, and Cancer but Not Neurodegenerative and Cardiovascular Diseases Strongly Modulate Systemic Effect of the Apolipoprotein E4 Allele on Lifespan

Enduring interest in the Apolipoprotein E (ApoE) polymorphism is ensured by its evolutionary-driven uniqueness in humans and its prominent role in geriatrics and gerontology. We use large samples of longitudinally followed populations from the Framingham Heart Study (FHS) original and offspring coho...

Descripción completa

Detalles Bibliográficos
Autores principales: Kulminski, Alexander M., Arbeev, Konstantin G., Culminskaya, Irina, Arbeeva, Liubov, Ukraintseva, Svetlana V., Stallard, Eric, Christensen, Kaare, Schupf, Nicole, Province, Michael A., Yashin, Anatoli I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907310/
https://www.ncbi.nlm.nih.gov/pubmed/24497847
http://dx.doi.org/10.1371/journal.pgen.1004141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907310/
https://www.ncbi.nlm.nih.gov/pubmed/24497847
http://dx.doi.org/10.1371/journal.pgen.1004141

Ejemplares similares