Parasite-Antigen Driven Expansion of IL-5(−) and IL-5(+) Th2 Human Subpopulations in Lymphatic Filariasis and Their Differential Dependence on IL-10 and TGFβ

BACKGROUND: Two different Th2 subsets have been defined recently on the basis of IL-5 expression – an IL-5(+)Th2 subset and an IL-5(−)Th2 subset in the setting of allergy. However, the role of these newly described CD4(+) T cells subpopulations has not been explored in other contexts. METHODS: To st...

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Detalles Bibliográficos
Autores principales: Anuradha, Rajamanickam, George, Parakkal Jovvian, Hanna, Luke E., Chandrasekaran, Vedachalam, Kumaran, P. Paul, Nutman, Thomas B., Babu, Subash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907332/
https://www.ncbi.nlm.nih.gov/pubmed/24498448
http://dx.doi.org/10.1371/journal.pntd.0002658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907332/
https://www.ncbi.nlm.nih.gov/pubmed/24498448
http://dx.doi.org/10.1371/journal.pntd.0002658

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