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WNT7B Promotes Bone Formation in part through mTORC1

WNT signaling has been implicated in both embryonic and postnatal bone formation. However, the pertinent WNT ligands and their downstream signaling mechanisms are not well understood. To investigate the osteogenic capacity of WNT7B and WNT5A, both normally expressed in the developing bone, we engine...

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Detalles Bibliográficos
Autores principales: Chen, Jianquan, Tu, Xiaolin, Esen, Emel, Joeng, Kyu Sang, Lin, Congxin, Arbeit, Jeffrey M., Rüegg, Markus A., Hall, Michael N., Ma, Liang, Long, Fanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907335/
https://www.ncbi.nlm.nih.gov/pubmed/24497849
http://dx.doi.org/10.1371/journal.pgen.1004145