Cargando…

Investigation of Acetylcholine Receptor Diversity in a Nematode Parasite Leads to Characterization of Tribendimidine- and Derquantel-Sensitive nAChRs

Nicotinic acetylcholine receptors (nAChRs) of parasitic nematodes are required for body movement and are targets of important “classical” anthelmintics like levamisole and pyrantel, as well as “novel” anthelmintics like tribendimidine and derquantel. Four biophysical subtypes of nAChR have been obse...

Descripción completa

Detalles Bibliográficos
Autores principales: Buxton, Samuel K., Charvet, Claude L., Neveu, Cedric, Cabaret, Jacques, Cortet, Jacques, Peineau, Nicolas, Abongwa, Melanie, Courtot, Elise, Robertson, Alan P., Martin, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907359/
https://www.ncbi.nlm.nih.gov/pubmed/24497826
http://dx.doi.org/10.1371/journal.ppat.1003870