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Investigation of Acetylcholine Receptor Diversity in a Nematode Parasite Leads to Characterization of Tribendimidine- and Derquantel-Sensitive nAChRs
Nicotinic acetylcholine receptors (nAChRs) of parasitic nematodes are required for body movement and are targets of important “classical” anthelmintics like levamisole and pyrantel, as well as “novel” anthelmintics like tribendimidine and derquantel. Four biophysical subtypes of nAChR have been obse...
Autores principales: | Buxton, Samuel K., Charvet, Claude L., Neveu, Cedric, Cabaret, Jacques, Cortet, Jacques, Peineau, Nicolas, Abongwa, Melanie, Courtot, Elise, Robertson, Alan P., Martin, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907359/ https://www.ncbi.nlm.nih.gov/pubmed/24497826 http://dx.doi.org/10.1371/journal.ppat.1003870 |
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