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Reengineering Redox Sensitive GFP to Measure Mycothiol Redox Potential of Mycobacterium tuberculosis during Infection

Mycobacterium tuberculosis (Mtb) survives under oxidatively hostile environments encountered inside host phagocytes. To protect itself from oxidative stress, Mtb produces millimolar concentrations of mycothiol (MSH), which functions as a major cytoplasmic redox buffer. Here, we introduce a novel sys...

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Detalles Bibliográficos
Autores principales: Bhaskar, Ashima, Chawla, Manbeena, Mehta, Mansi, Parikh, Pankti, Chandra, Pallavi, Bhave, Devayani, Kumar, Dhiraj, Carroll, Kate S., Singh, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907381/
https://www.ncbi.nlm.nih.gov/pubmed/24497832
http://dx.doi.org/10.1371/journal.ppat.1003902