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Axonal trafficking of NMNAT2 and its roles in axon growth and survival in vivo

The NAD-synthesizing enzyme NMNAT2 is critical for axon survival in primary culture and its depletion may contribute to axon degeneration in a variety of neurodegenerative disorders. Here we discuss several recent reports from our laboratory that establish a critical role for NMNAT2 in axon growth i...

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Detalles Bibliográficos
Autores principales: Milde, Stefan, Gilley, Jonathan, Coleman, Michael P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907460/
https://www.ncbi.nlm.nih.gov/pubmed/24284888
http://dx.doi.org/10.4161/bioa.27049