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Axonal trafficking of NMNAT2 and its roles in axon growth and survival in vivo
The NAD-synthesizing enzyme NMNAT2 is critical for axon survival in primary culture and its depletion may contribute to axon degeneration in a variety of neurodegenerative disorders. Here we discuss several recent reports from our laboratory that establish a critical role for NMNAT2 in axon growth i...
Autores principales: | Milde, Stefan, Gilley, Jonathan, Coleman, Michael P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907460/ https://www.ncbi.nlm.nih.gov/pubmed/24284888 http://dx.doi.org/10.4161/bioa.27049 |
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