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Sleep Fragmentation Promotes NADPH Oxidase 2-Mediated Adipose Tissue Inflammation Leading to Insulin Resistance in Mice

BACKGROUND: Short sleep has been implicated in higher risk of obesity in humans, and is associated with insulin resistance. However, the effects of fragmented sleep (SF) rather than curtailed sleep on glucose homeostasis are unknown. METHODS: Wild type and NADPH oxidase 2 (Nox2) null male mice were...

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Detalles Bibliográficos
Autores principales: Zhang, Shelley X.L., Khalyfa, Abdelnaby, Wang, Yang, Carreras, Alba, Hakim, Fahed, Neel, Brian A., Brady, Matthew J., Qiao, Zhuanhong, Hirotsu, Camila, Gozal, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907464/
https://www.ncbi.nlm.nih.gov/pubmed/23897221
http://dx.doi.org/10.1038/ijo.2013.139