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The Modulation of Endoplasmic Reticulum Stress by Chemical Chaperone Upregulates Immune Negative Cytokine IL-35 in Apolipoprotein E-Deficient Mice

Interleukin (IL)-35 is a newly identified immune negative molecule which is secreted by CD4(+)Foxp3(+) T regulatory cells (Tregs) and contributes to their suppressive capacity. Early data have shown that IL-35 inhibits development of several autoimmune diseases. However, the role of IL-35 in atheros...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Dai, Shen, Dong, Zhaojing, Sun, Yue, Song, Xingguo, Guo, Chun, Zhu, Faliang, Wang, Qun, Zhang, Lining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907489/
https://www.ncbi.nlm.nih.gov/pubmed/24498194
http://dx.doi.org/10.1371/journal.pone.0087787