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Chloroquine Stimulates Cl(−) Secretion by Ca(2+) Activated Cl(−) Channels in Rat Ileum

Chloroquine (CQ), a bitter tasting drug widely used in treatment of malaria, is associated gastrointestinal side effects including nausea or diarrhea. In the present study, we investigated the effect of CQ on electrolyte transport in rat ileum using the Ussing chamber technique. The results showed t...

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Detalles Bibliográficos
Autores principales: Yang, Ning, Lei, Zhen, Li, Xiaoyu, Zhao, Junhan, Liu, Tianjian, Ning, Nannan, Xiao, Ailin, Xu, Linlin, Li, Jingxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907514/
https://www.ncbi.nlm.nih.gov/pubmed/24498157
http://dx.doi.org/10.1371/journal.pone.0087627