Mitochondrial DNA 10609T Promotes Hypoxia-Induced Increase of Intracellular ROS and Is a Risk Factor of High Altitude Polycythemia

Hypobaric hypoxia is the primary cause of high altitude polycythemia (HAPC). Mitochondria are critical organelles that consume high levels of oxygen and generate ATP. We hypothesize that the mitochondrion may be at the center of HAPC, and mitochondrial DNA (mtDNA) SNPs may be involved in its develop...

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Detalles Bibliográficos
Autores principales: Jiang, Chunhua, Cui, Jianhua, Liu, Fuyu, Gao, Liang, Luo, Yongjun, Li, Peng, Guan, Libin, Gao, Yuqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907523/
https://www.ncbi.nlm.nih.gov/pubmed/24498190
http://dx.doi.org/10.1371/journal.pone.0087775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907523/
https://www.ncbi.nlm.nih.gov/pubmed/24498190
http://dx.doi.org/10.1371/journal.pone.0087775

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