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GNAS Mutations Identify a Set of Right-Sided, RAS Mutant, Villous Colon Cancers

The purpose of this study is to determine the genetic frequency of GNAS activating mutations in colorectal cancer and the corresponding pathology of GNAS mutant tumors. Oncogenic mutations in GNAS have been described in a number of neoplasms including those of the pituitary, kidney, pancreas, and, m...

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Detalles Bibliográficos
Autores principales: Fecteau, Ryan E., Lutterbaugh, James, Markowitz, Sanford D., Willis, Joseph, Guda, Kishore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907576/
https://www.ncbi.nlm.nih.gov/pubmed/24498230
http://dx.doi.org/10.1371/journal.pone.0087966