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Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection

BACKGROUND: Human Endogenous Retroviruses (HERVs) comprise about 8% of the human genome and have lost their ability to replicate or to produce infectious particles after having accumulated mutations over time. We assessed the kinetics of expression of HERV-K (HML-2) Envelope mRNA transcript and surf...

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Detalles Bibliográficos
Autores principales: Michaud, Henri-Alexandre, de Mulder, Miguel, SenGupta, Devi, Deeks, Steven G, Martin, Jeffrey N, Pilcher, Christopher D, Hecht, Frederick M, Sacha, Jonah B, Nixon, Douglas F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907665/
https://www.ncbi.nlm.nih.gov/pubmed/24472118
http://dx.doi.org/10.1186/1742-4690-11-10