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Late onset deficits in synaptic plasticity in the valproic acid rat model of autism

Valproic acid (VPA) is a frequently used drug in the treatment of epilepsy, bipolar disorders and migraines; however it is also a potent teratogen. Prenatal exposure increases the risk of childhood malformations and can result in cognitive deficits. In rodents in utero exposure to VPA also causes ne...

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Detalles Bibliográficos
Autores principales: Martin, Henry G. S., Manzoni, Olivier J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907704/
https://www.ncbi.nlm.nih.gov/pubmed/24550781
http://dx.doi.org/10.3389/fncel.2014.00023