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Late onset deficits in synaptic plasticity in the valproic acid rat model of autism
Valproic acid (VPA) is a frequently used drug in the treatment of epilepsy, bipolar disorders and migraines; however it is also a potent teratogen. Prenatal exposure increases the risk of childhood malformations and can result in cognitive deficits. In rodents in utero exposure to VPA also causes ne...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907704/ https://www.ncbi.nlm.nih.gov/pubmed/24550781 http://dx.doi.org/10.3389/fncel.2014.00023 |