Effects of a newly developed potent orexin-2 receptor-selective antagonist, compound 1 m, on sleep/wakefulness states in mice

Orexins (also known as hypocretins) play critical roles in the regulation of sleep/wakefulness states by activating two G-protein coupled receptors (GPCRs), orexin 1 (OX(1)R) and orexin 2 receptors (OX(2)R). In order to understand the differential contribution of both receptors in regulating sleep/w...

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Detalles Bibliográficos
Autores principales: Etori, Keishi, Saito, Yuki C., Tsujino, Natsuko, Sakurai, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907770/
https://www.ncbi.nlm.nih.gov/pubmed/24550770
http://dx.doi.org/10.3389/fnins.2014.00008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907770/
https://www.ncbi.nlm.nih.gov/pubmed/24550770
http://dx.doi.org/10.3389/fnins.2014.00008

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