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Ranking and compacting binding segments of protein families using aligned pattern clusters

BACKGROUND: Discovering sequence patterns with variation can unveil functions of a protein family that are important for drug discovery. Exploring protein families using existing methods such as multiple sequence alignment is computationally expensive, thus pattern search, called motif finding in Bi...

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Detalles Bibliográficos
Autores principales: Lee, En-Shiun Annie, Wong, Andrew KC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907781/
https://www.ncbi.nlm.nih.gov/pubmed/24564874
http://dx.doi.org/10.1186/1477-5956-11-S1-S8