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Biochemical reconstitution of topological DNA binding by the cohesin ring

Cohesion between sister chromatids, mediated by the chromosomal cohesin complex, is a prerequisite for faithful chromosome segregation in mitosis. Cohesin plays vital roles also in DNA repair and transcriptional regulation. The ring-shaped cohesin complex is thought to encircle sister DNA strands, b...

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Detalles Bibliográficos
Autores principales:	Murayama, Yasuto, Uhlmann, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907785/ https://www.ncbi.nlm.nih.gov/pubmed/24291789 http://dx.doi.org/10.1038/nature12867

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