Lenalidomide overcomes suppression of human natural killer cell anti-tumor functions by neuroblastoma microenvironment-associated IL-6 and TGFβ1

BACKGROUND: Treatment for children with high-risk neuroblastoma with anti-disialoganglioside mAb ch14.18, IL-2, and GM-CSF plus 13-cis-retinoic acid after myeloablative chemotherapy improves survival, but 40 % of patients still relapse during or after this therapy. The microenvironment of high-risk...

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Detalles Bibliográficos
Autores principales: Xu, Yibing, Sun, Jianping, Sheard, Michael A., Tran, Hung C., Wan, Zesheng, Liu, Wei Yao, Asgharzadeh, Shahab, Sposto, Richard, Wu, Hong Wei, Seeger, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907789/
https://www.ncbi.nlm.nih.gov/pubmed/23982484
http://dx.doi.org/10.1007/s00262-013-1466-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907789/
https://www.ncbi.nlm.nih.gov/pubmed/23982484
http://dx.doi.org/10.1007/s00262-013-1466-y

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