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Phenoxybenzamine Is Neuroprotective in a Rat Model of Severe Traumatic Brain Injury
Phenoxybenzamine (PBZ) is an FDA approved α-1 adrenergic receptor antagonist that is currently used to treat symptoms of pheochromocytoma. However, it has not been studied as a neuroprotective agent for traumatic brain injury (TBI). While screening neuroprotective candidates, we found that phenoxybe...
Autores principales: | Rau, Thomas F., Kothiwal, Aakriti, Rova, Annela, Rhoderick, Joseph F., Poulsen, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907876/ https://www.ncbi.nlm.nih.gov/pubmed/24447929 http://dx.doi.org/10.3390/ijms15011402 |
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