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Phosphorylation of Histone H2AX in the Mouse Brain from Development to Senescence

Phosphorylation of the histone H2AX (γH2AX form) is an early response to DNA damage and a marker of aging and disease in several cells and tissues outside the nervous system. Little is known about in vivo phosphorylation of H2AX in neurons, although it was suggested that γH2AX is an early marker of...

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Detalles Bibliográficos
Autores principales: Barral, Serena, Beltramo, Riccardo, Salio, Chiara, Aimar, Patrizia, Lossi, Laura, Merighi, Adalberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907886/
https://www.ncbi.nlm.nih.gov/pubmed/24451138
http://dx.doi.org/10.3390/ijms15011554