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Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells

Although mesenchymal stem cells (MSCs) play pivotal supportive roles in hematopoiesis, how they interact with hematopoietic stem cells (HSCs) is not well understood. We investigated the interaction between HSCs and surrogate MSCs (C3H10T1/2 stromal cells), focusing on the molecular events induced by...

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Detalles Bibliográficos
Autores principales: Kikuchi, Y, Kume, A, Urabe, M, Mizukami, H, Suzuki, T, Ozaki, K, Nagai, T, Ozawa, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Stem cells and Regenerative Medicine 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908275/
https://www.ncbi.nlm.nih.gov/pubmed/24693172