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Residue correlation networks in nuclear receptors reflect functional specialization and the formation of the nematode-specific P-box

BACKGROUND: Nuclear receptors (NRs) are transcription factors which bind small hormones, whose evolutionary history and the presence of different functional surfaces makes them an interesting target for a correlation based analysis. RESULTS: Correlation analysis of ligand binding domains shows that...

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Detalles Bibliográficos
Autores principales: Lima Afonso, Marcelo Querino, de Lima, Leonardo Henrique França, Bleicher, Lucas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908500/
https://www.ncbi.nlm.nih.gov/pubmed/24564869
http://dx.doi.org/10.1186/1471-2164-14-S6-S1