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An effective and effecient peptide binding prediction approach for a broad set of HLA-DR molecules based on ordered weighted averaging of binding pocket profiles

BACKGROUND: The immune system must detect a wide variety of microbial pathogens, such as viruses, bacteria, fungi and parasitic worms, to protect the host against disease. Antigenic peptides displayed by MHC II (class II Major Histocompatibility Complex) molecules is a pivotal process to activate CD...

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Detalles Bibliográficos
Autores principales: Shen, Wen-Jun, Zhang, Shaohong, Wong, Hau-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908610/
https://www.ncbi.nlm.nih.gov/pubmed/24565049
http://dx.doi.org/10.1186/1477-5956-11-S1-S15