A combination of SILAC and nucleotide acyl phosphate labelling reveals unexpected targets of the Rsk inhibitor BI-D1870

Protein kinase inhibitors frequently have interesting effects that cannot be fully ascribed to the intended target kinase(s) but identifying additional targets that might explain the effects is not straightforward. By comparing two different inhibitors of the Rsk (p90 ribosomal S6 kinase) kinases, w...

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Detalles Bibliográficos
Autores principales: Edgar, Alexander J., Trost, Matthias, Watts, Colin, Zaru, Rossana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908613/
https://www.ncbi.nlm.nih.gov/pubmed/27919044
http://dx.doi.org/10.1042/BSR20130094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908613/
https://www.ncbi.nlm.nih.gov/pubmed/27919044
http://dx.doi.org/10.1042/BSR20130094

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