Ceftazidime–avibactam: an evidence-based review of its pharmacology and potential use in the treatment of Gram-negative bacterial infections

Avibactam (NXL104, AVE1330A) is a semi-synthetic, non-β-lactam, β-lactamase inhibitor that is active against Ambler class A, class C, and some class D serine β-lactamases. In this review, we summarize the in vitro data, pharmacology, mechanisms of action and resistance, and clinical trial data relat...

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Detalles Bibliográficos
Autores principales: Lagacé-Wiens, Philippe, Walkty, Andrew, Karlowsky, James A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908787/
https://www.ncbi.nlm.nih.gov/pubmed/24493994
http://dx.doi.org/10.2147/CE.S40698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908787/
https://www.ncbi.nlm.nih.gov/pubmed/24493994
http://dx.doi.org/10.2147/CE.S40698

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