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Genetic Diversity of the KIR/HLA System and Outcome of Patients with Metastatic Colorectal Cancer Treated with Chemotherapy

OBJECTIVE: To explore genes of the killer-cell immunoglobulin-like receptor (KIR) and of the HLA ligand and their relationship with the outcome of metastatic colorectal cancer (mCRC) patients treated with first-line 5-fluorouracil, leucovorin, and irinotecan (FOLFIRI). METHODS: A total of 224 mCRC p...

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Detalles Bibliográficos
Autores principales: De Re, Valli, Caggiari, Laura, De Zorzi, Mariangela, Talamini, Renato, Racanelli, Vito, Andrea, Mario D’, Buonadonna, Angela, Zagonel, Vittorina, Cecchin, Erika, Innocenti, Federico, Toffoli, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908861/
https://www.ncbi.nlm.nih.gov/pubmed/24497922
http://dx.doi.org/10.1371/journal.pone.0084940