Cobalt and Nickel Stabilize Stem Cell Transcription Factor OCT4 through Modulating Its Sumoylation and Ubiquitination

Stem cell research can lead to the development of treatments for a wide range of ailments including diabetes, heart disease, aging, neurodegenerative diseases, spinal cord injury, and cancer. OCT4 is a master regulator of self-renewal of undifferentiated embryonic stem cells. OCT4 also plays a cruci...

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Detalles Bibliográficos
Autores principales: Yao, Yixin, Lu, Yinghua, Chen, Wen-chi, Jiang, Yongping, Cheng, Tao, Ma, Yupo, Lu, Lou, Dai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908935/
https://www.ncbi.nlm.nih.gov/pubmed/24497960
http://dx.doi.org/10.1371/journal.pone.0086620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908935/
https://www.ncbi.nlm.nih.gov/pubmed/24497960
http://dx.doi.org/10.1371/journal.pone.0086620

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