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Humoral Immune Responses to EGFR-Derived Peptides Predict Progression-Free and Overall Survival of Non-Small Cell Lung Cancer Patients Receiving Gefitinib

Somatic mutations in the epidermal growth factor receptor (EGFR) gene are associated with clinical response to EGFR tyrosine kinase inhibitors (TKIs), such as gefitinib, in patients with non-small cell lung cancer (NSCLC). However, humoral immune responses to EGFR in NSCLC patients have not been wel...

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Detalles Bibliográficos
Autores principales: Azuma, Koichi, Komatsu, Nobukazu, Hattori, Satoshi, Matsueda, Satoko, Kawahara, Akihiko, Sasada, Tetsuro, Itoh, Kyogo, Hoshino, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909003/
https://www.ncbi.nlm.nih.gov/pubmed/24497964
http://dx.doi.org/10.1371/journal.pone.0086667