Three New Genetic Loci (R1210C in CFH, Variants in COL8A1 and RAD51B) Are Independently Related to Progression to Advanced Macular Degeneration

OBJECTIVES: To assess the independent impact of new genetic variants on conversion to advanced stages of AMD, controlling for established risk factors, and to determine the contribution of genes in predictive models. METHODS: In this prospective longitudinal study of 2765 individuals, 777 subjects p...

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Detalles Bibliográficos
Autores principales: Seddon, Johanna M., Reynolds, Robyn, Yu, Yi, Rosner, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909074/
https://www.ncbi.nlm.nih.gov/pubmed/24498017
http://dx.doi.org/10.1371/journal.pone.0087047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909074/
https://www.ncbi.nlm.nih.gov/pubmed/24498017
http://dx.doi.org/10.1371/journal.pone.0087047

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