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Three New Genetic Loci (R1210C in CFH, Variants in COL8A1 and RAD51B) Are Independently Related to Progression to Advanced Macular Degeneration
OBJECTIVES: To assess the independent impact of new genetic variants on conversion to advanced stages of AMD, controlling for established risk factors, and to determine the contribution of genes in predictive models. METHODS: In this prospective longitudinal study of 2765 individuals, 777 subjects p...
Autores principales: | Seddon, Johanna M., Reynolds, Robyn, Yu, Yi, Rosner, Bernard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909074/ https://www.ncbi.nlm.nih.gov/pubmed/24498017 http://dx.doi.org/10.1371/journal.pone.0087047 |
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