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Epigenetic Suppression of Mouse Per2 Expression in the Suprachiasmatic Nucleus by the Inhalational Anesthetic, Sevoflurane

BACKGROUND: We previously reported that sevoflurane anesthesia reversibly suppresses the expression of the clock gene, Period2 (Per2), in the mouse suprachiasmatic nucleus (SCN). However, the molecular mechanisms underlying this suppression remain unclear. In this study, we examined the possibility...

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Detalles Bibliográficos
Autores principales: Mori, Keisuke, Iijima, Norio, Higo, Shimpei, Aikawa, Satoko, Matsuo, Izumi, Takumi, Ken, Sakamoto, Atsuhiro, Ozawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909093/
https://www.ncbi.nlm.nih.gov/pubmed/24498074
http://dx.doi.org/10.1371/journal.pone.0087319