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The Calpain Inhibitor MDL28170 Induces the Expression of Apoptotic Markers in Leishmania amazonensis Promastigotes

BACKGROUND: Human cutaneous leishmaniasis is caused by distinct species, including Leishmania amazonensis. Treatment of cutaneous leishmaniasis is far from satisfactory due to increases in drug resistance and relapses, and toxicity of compounds to the host. As a consequence for this situation, the d...

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Detalles Bibliográficos
Autores principales: Marinho, Fernanda A., Gonçalves, Keyla C. S., Oliveira, Simone S. C., Gonçalves, Diego S., Matteoli, Filipe P., Seabra, Sergio H., Oliveira, Ana Carolina S., Bellio, Maria, Oliveira, Selma S., Souto-Padrón, Thaïs, d'Avila-Levy, Claudia M., Santos, André L. S., Branquinha, Marta H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909198/
https://www.ncbi.nlm.nih.gov/pubmed/24498160
http://dx.doi.org/10.1371/journal.pone.0087659