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The Calpain Inhibitor MDL28170 Induces the Expression of Apoptotic Markers in Leishmania amazonensis Promastigotes
BACKGROUND: Human cutaneous leishmaniasis is caused by distinct species, including Leishmania amazonensis. Treatment of cutaneous leishmaniasis is far from satisfactory due to increases in drug resistance and relapses, and toxicity of compounds to the host. As a consequence for this situation, the d...
Autores principales: | Marinho, Fernanda A., Gonçalves, Keyla C. S., Oliveira, Simone S. C., Gonçalves, Diego S., Matteoli, Filipe P., Seabra, Sergio H., Oliveira, Ana Carolina S., Bellio, Maria, Oliveira, Selma S., Souto-Padrón, Thaïs, d'Avila-Levy, Claudia M., Santos, André L. S., Branquinha, Marta H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909198/ https://www.ncbi.nlm.nih.gov/pubmed/24498160 http://dx.doi.org/10.1371/journal.pone.0087659 |
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