Targeting Innate Receptors with MIS416 Reshapes Th Responses and Suppresses CNS Disease in a Mouse Model of Multiple Sclerosis

Modification of the innate immune cell environment has recently been recognized as a viable treatment strategy for reducing autoimmune disease pathology. MIS416 is a microparticulate immune response modifier that targets myeloid cells, activating cytosolic receptors NOD2 and TLR9, and has completed...

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Detalles Bibliográficos
Autores principales: White, Madeleine, Webster, Gill, O’Sullivan, David, Stone, Sarrabeth, La Flamme, Anne Camille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909208/
https://www.ncbi.nlm.nih.gov/pubmed/24498172
http://dx.doi.org/10.1371/journal.pone.0087712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909208/
https://www.ncbi.nlm.nih.gov/pubmed/24498172
http://dx.doi.org/10.1371/journal.pone.0087712

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