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Enlarged Memory T-Cell Pool and Enhanced Th1-Type Responses in Chronic Myeloid Leukemia Patients Who Have Successfully Discontinued IFN-α Monotherapy

A small proportion of chronic myeloid leukemia patients treated with interferon-α (IFN-α) monotherapy are able to discontinue the treatment without disease relapse although residual leukemia cells are present. Recently, we showed that these patients have increased amount of NK-cells and a distinct b...

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Detalles Bibliográficos
Autores principales: Ilander, Mette, Kreutzman, Anna, Rohon, Peter, Melo, Teresa, Faber, Edgar, Porkka, Kimmo, Vakkila, Jukka, Mustjoki, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909235/
https://www.ncbi.nlm.nih.gov/pubmed/24498197
http://dx.doi.org/10.1371/journal.pone.0087794