ERK MAP Kinase Activation in Spinal Cord Regulates Phosphorylation of Cdk5 at Serine 159 and Contributes to Peripheral Inflammation Induced Pain/Hypersensitivity

Cyclin-dependent kinase 5 is a proline-directed serine/threonine kinase and its activity participates in the regulation of nociceptive signaling. Like binding with the activators (P35 or P25), the phosphorylation of Cdk5 plays a critical role in Cdk5 activation. However, it is still unclear whether...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiaoqin, Zhang, Honghai, Shao, Haijun, Xue, Qingsheng, Yu, Buwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909239/
https://www.ncbi.nlm.nih.gov/pubmed/24498195
http://dx.doi.org/10.1371/journal.pone.0087788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909239/
https://www.ncbi.nlm.nih.gov/pubmed/24498195
http://dx.doi.org/10.1371/journal.pone.0087788

Ejemplares similares